About CYTOCON DB Open


CYTOCON (Cell and cYTOkine CONcentrations) is an initiative project undertaken by InSysBio team and aimed at the development of a database that allows collecting, processing and visualizing publicly available data on immune cells and cytokine baseline concentrations in humans.

CYTOCON DB is a database of human baseline concentrations of cytokines and cells measured in different tissues of healthy subjects and patients suffering from various pathologies. 

CYTOCON DB is accessible via purchasing the commercial license. You can visit www.cytocon.insysbio.com for more details. CYTOCON DB Open is reduced and free version of CYTOCON DB designed for public use. CYTOCON DB Open differs from CYTOCON DB in content and functional features of both front and back ends.

Both content and functionality of CYTOCON DB Open will be updated once per year.

Key features of CYTOCON DB Open:

  • Search for cell/cytokine concentration for selected disease, tissue (or a group of diseases and tissues), patient group.
  • Search query for cell concentration may include a list of cell markers: i.e. for Th2-cell - CD4+, IL4+
  • Search query may include following patient group attributes:
    • demographic characteristics (age, race, gender, etc);
    • number of patients in the study.
  • Search query may take into account disease-specific clinically measured characteristics, for example:
    • Asthma: FEV1;
    • SLE: SLEDAI range, interferon signature;
    • Atopic Dermatitis: SCORAD range, severity, range of IgE concentration;
    • etc.
  • Unification of measurement units: conversion of source original units to “pM” for cytokine and “kcell/L” for cell concentration.
  • Table representation of search results: average value and dispersion of concentration of cell/cytokine in original and unified units, tissue type, data source, patient group and disease attributes are specified.
  • Graphic representation of search results: average value, dispersion, source.
  • Export of search results in csv format

Content of CYTOCON DB Open version:

    • Acinic cell adenocarcinoma
    • Acute allergic reactions
    • Acute coronary syndrome
    • Acute coronary syndrome, nonocclusive type (unstable angina)
    • Acute coronary syndrome, occlusive type (transmural myocardial infarction)
    • Acute hepatitis B
    • Acute lymphoid leukaemia
    • Acute myeloid leukaemia
    • Acute pancreatitis
    • Acute pyelonephritis
    • Adenocarcinoma of bronchus or lung
    • Adenocarcinoma of cervix
    • Adenocarcinoma of oesophagus
    • Adenocarcinoma of stomach
    • Adenoid cystic carcinoma
    • Adenosquamous carcinoma of bronchus or lung
    • Adult T-cell leukaemia/lymphoma (ATLL)
    • adult-onset Still’s disease (AOSD)
    • AIDS
    • AIDS-related non-Hodgkin lymphoma
    • Alcohol-induced dementia
    • Allergic asthma
    • Allergic contact dermatitis
    • Allergic rhinitis
    • Alveolar rhabdomyosarcoma
    • Alveolar soft part sarcoma
    • Alzheimer disease
    • Angiosarcoma
    • Ankylosing spondylitis
    • Appendicitis and Diverticulitis
    • Asthma
    • Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS)
    • Atopic allergy
    • Atopic asthma
    • Atopic dermatitis
    • Atopy, nonasthma
    • Atrial fibrillation
    • Atypical autism (F84.1)
    • Atypical hyperplasia
    • Autism (F84.0)
    • Autism spectrum disorder
    • Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy
    • Bacterial pneumonia
    • Basal cell carcinoma
    • B-cell non-Hodgkin lymphoma (B-NHL)
    • Behçet's disease
    • Benign conditions of ovary and uterus
    • Benign lung lesions
    • Benign ovarian pathologies
    • Benign soft-tissue neoplasm
    • Brain trauma
    • Breast cancer
    • Breast carcinoma
    • Bronchial asthma
    • Bronchiectasis
    • Bronchoalveolar carcinoma
    • Bullous pemphigoid
    • Carcinoma
    • CD40L deficiency
    • Celiac disease
    • Central nervous system infection
    • Cerebrovascular disease no-dementia
    • Cervical cancer
    • Cervical intraepithelial neoplasia
    • Chondrosarcoma
    • Chordoma
    • Chronic atrophic gastritis
    • Chronic Bronchial Asthma
    • Chronic bronchitis (COPD)
    • Chronic cough
    • Chronic hepatitis B
    • Chronic Hepatitis C
    • Chronic idiopathic urticaria, hives
    • Chronic kidney disease
    • Chronic liver failure (CLF)
    • Chronic myeloid leukaemia
    • Chronic obstructive pulmonary disease (COPD)
    • Chronic Spontaneous Urticaria
    • Chronic superficial gastritis
    • Clear cell sarcoma
    • Coeliac disease
    • Colitis
    • Colitis associated cancer (CAC)
    • Colon adenocarcinoma
    • Colon carcinoma
    • Colonic cancer
    • Colorectal cancer (CRC)
    • Common variable immunodeficiency (CVID)
    • Contact dermatitis
    • COVID-19
    • Crohn's disease
    • Cutaneous Lupus Erythematosus
    • Cutaneous T-cell lymphoma
    • Cyclic neutropenia
    • Cystic fibrosis
    • Dedifferentiated liposarcoma
    • Deep vein thrombosis
    • Dementia with Lewy bodies (DLB)
    • Dengue
    • Depression (6A70.Z Single episode depressive disorder)
    • Dermatomyositis
    • Dermatophytosis
    • Desmoplastic small round cell tumour
    • DFSP dermatofibrosarcoma protuberans
    • Discoid Lupus Erythematosus
    • Dysbacteriosis
    • Dysmyelopoiesis
    • Early arthritis
    • Embryonal rhabdomyosarcoma
    • End stage renal disease
    • Endometrial carcinoma
    • Endometriosis
    • Enthesitis-related arthritis
    • Eosinophilia
    • Eosinophilic asthma
    • Eosinophilic bronchitis
    • Epithelioid sarcoma
    • Epstein-Barr virus (EBV) infection
    • Erythema multiforme
    • Esophageal cancer
    • Esophageal carcinoma
    • Ewing sarcoma
    • Familial lecithin:cholesterol acyltransferase (LCAT) deficiency
    • Familial lipoprotein lipase (LPL) deficiency
    • Fanconi anaemia
    • Fibrotic hypersensitivity pneumonitis
    • Focal segmental glomerulosclerosis
    • Follicular lymphoma
    • Frontotemporal lobe dementia (FTLD)
    • Gastric cancer
    • Gastric ulcer
    • GIST gastrointestinal stromal tumour
    • Gout
    • HBV carriers
    • HBV-related cirrhosis
    • HBV-related HCC (hepatocellular carcinoma)
    • Head and neck cancer
    • Head and Neck Squamous Cell Carcinoma
    • Healthy control
    • Hepatitis B
    • Hepatitis non-infectious
    • Hepatocellular carcinoma (HCC)
    • Human imunodeficiency virus (HIV-1) infection
    • Idiopathic aplastic anemia
    • Idiopathic inflammatory myopathies
    • Idiopathic interstitial pneumonia
    • Idiopathic pulmonary fibrosis
    • IgA glomerulonephriris
    • Immunoglobulin A nephropathy (IgAN)
    • Infections
    • Inflammatory Bowel Diseases
    • Inflammatory breast cancer (IBC)
    • Influenza
    • Interstitial pneumonia with autoimmune features
    • Irritable Bowel Syndrome
    • Juvenile idiopathic arthritis
    • Large cell carcinoma of bronchus or lung
    • Laryngeal papilloma
    • Laryngeal Squamous Cell Carcinoma
    • Leiomyosarcoma
    • Liver cirrhosis
    • Low-grade fibromyxoid sarcoma
    • Lung cancer
    • Lupus nephritis
    • Lymphadenopathic mastocytosis with eosinophilia
    • Malignant salivary gland tumors
    • Melanoma
    • Membranous nephropathy
    • Microcrystal arthritis
    • Mild cognitive impairment (MCI)
    • Mild cognitive impairment with Alzheimer’s disease (MCI-AD)
    • Mild cognitive impairment with Lewy body dementia (MCI-LB)
    • Minimal change disease (MCD, minimal change glomerulopathy)
    • Mixed granulocytic asthma
    • MPNST malignant peripheral nerve sheath tumor
    • Mucoepidermoid carcinoma
    • Multiple myeloma
    • Multiple sclerosis
    • Myasthenia gravis
    • Myelodysplastic syndrome
    • Myoma
    • Myxofibrosarcoma
    • Myxoid/round cell liposarcoma (MRCL)
    • Neutrophilic asthma
    • Nocturnal Asthma
    • Non-atopic asthma
    • Non-eosinophilic asthma
    • Non-fibrotic lung diseases
    • Non-Hodgkin Lymphoma
    • Non-Hodgkin's lymphoma and Hodgkin's lymhoma patients
    • Non-idiopathic pulmonary fibrosis
    • Non-psoriatic arthritis spondyloarthritis (non-PsA SpA)
    • Non-Small Cell Lung Cancer (NSCLC)
    • Non-squamous bronchial carcinoma
    • Non-translocation sarcoma
    • Novel coronavirus pneumonia
    • Nummular Eczema
    • Obesity
    • Oral lichen planus
    • Oral submucous fibrosis
    • Osteoarthritis
    • Osteoarthritis inflammatory
    • Osteosarcoma
    • Ovarian cancer
    • Pancreatic cancer
    • Parotid gland acinic cell carcinoma
    • Parotid gland myoepithelioma
    • Parotid gland pleomorphic adenoma
    • Parotid gland Warthin’s tumor
    • Paucigranulocytic asthma
    • Pemphigus vulgaris
    • Pleomorphic adenoma
    • Pneumonia
    • Polycythaemia vera
    • Primary bronchial carcinoma
    • Progressive supranuclear palsy (PSP)
    • Prostate cancer
    • Psoriasis
    • Psoriatic arthritis
    • Pulmonary embolism
    • Pulmonary emphysema
    • Reactive arthritis
    • Recurrent depressive disorders
    • Refractory Bone and Soft Tissue Sarcoma
    • Relapsing polychondritis
    • Renal carcinoma
    • Renal cell carcinoma
    • Renal dysfunction
    • Respiratory syncytial virus (RSV) pneumonia
    • Rheumatoid arthritis
    • Sarcoidosis
    • Sarcoma
    • Schizophrenia
    • Sclerodermia
    • Sclerosing lymphocytic lobulitis of the breast
    • Seborrheic dermatitis
    • Sepsis
    • Septic shock
    • Sjogrens syndrome
    • Skin cancer
    • Small cell carcinoma of bronchus or lung
    • Small cell lung cancer (SCLC)
    • Soft tissue sarcoma
    • Solid malignant tumors
    • Solitary fibrous tumor
    • Spondyloarthritis
    • Spondyloarthropathy
    • Sporadic colorectal cancer (SCRC)
    • Squamous cell carcinoma of bronchus or lung
    • Squamous cell carcinoma of cervix
    • Squamous cell carcinoma of oesophagus
    • Stable angina
    • Stable coronary artery disease (SCAD)
    • Stat3-Hyper-IgE syndrome
    • Stress-induced (Takotsubo) cardiomyopathy
    • Symptomatic cartilage defects
    • Synovial sarcoma
    • System indolent mastocytosis
    • Systemic lupus erythematosus
    • Systemic onset juvenile idiopathic arthritis
    • Thrombocytopenia
    • Thrombocytosis
    • Thyroid adenoma
    • Thyroid cancer
    • Thyroid carcinoma
    • Translocation-associated sarcoma
    • Traumatic ulcers
    • Tuberculosis
    • Ulcerative colitis
    • Undifferentiated arthritis
    • Unexplained recurrent anaphylaxis
    • Upper gastrointestinal cancers
    • UPS undifferentiated pleomorphic sarcoma
    • Urinary tract infection
    • Urticaria pigmentosa
    • Uterine cervical cancer
    • Vascular dementia
    • Viral meningoencephalitis
    • Wegener’s granuloma
    • Well-differentiated liposarcoma
    • Adenocarcinoma of oesophagus tumor tissue
    • Airway (bronchial) epithelium
    • Airway lamina propria
    • Airway smooth muscle
    • Airways adventitia
    • Airways basement membrane
    • Ascending colon lamina propria
    • Basement membrane of epidermis
    • Basement membrane of epidermis lesional
    • Basement membrane of epidermis nonlesional
    • Benign lung lesion homogenates
    • Blood
    • Blood arterial
    • Blood from tumor
    • Bone marrow
    • Bone marrow blood
    • Bone marrow plasma
    • Brain tissue lysate (BA21)
    • Breast cancer tumor tissue
    • Breast intra-ductal region
    • Breast intra-lobular region
    • Breast parenchyma
    • Breast peri-ductal region
    • Breast peri-lobular region
    • Breast peri-vascular region
    • Bronchial glands
    • Bronchial mucosa
    • Bronchial subepithelial tissue
    • Bronchial submucosa
    • Bronchial tissue
    • Bronchial wash
    • Bronchoalveolar carcinoma tumor tissue
    • Broncho-alveolar lavage (BAL)
    • Caecum lamina propria
    • Caecum lymphoid aggregates
    • Caecum mucosa
    • Cartilage
    • Cerebrospinal fluid (CSF)
    • Cervical tissue
    • Cervical tumor tissue
    • Colon
    • Colon epithelium
    • colon lamina propria lymphoid aggregates/solitary follicles
    • colon lamina propria outside lymphoid aggregates/solitary follicles
    • Colon mucosa
    • Colonic lamina propria
    • Colonic lymphoid follicles
    • Colorectal cancer tumor center
    • Colorectal cancer tumor invasive margin
    • Coproextracts
    • Dermis
    • Dermis papillary
    • Dermis papillary lesional
    • Dermis papillary nonlesional
    • Dermis upper
    • Dermis upper lesional
    • Dermis upper nonlesional
    • Descending colon mucosa
    • Distant metastasis
    • Duodenal lamina propria
    • Duodenal mucosa
    • Endobronchial (airway) biopsies
    • Epidermis
    • Epithelial lining fluid in airways
    • Esophageal cancer tumor tissue
    • Esophageal tumor tissue lysate
    • Exhaled Breath Condensate
    • Gastric tissue
    • Gastric tumor tissue
    • Gut-associated lymphoid tissue
    • HCC peritumoral stroma
    • HCC peritumoral tissue
    • Head and Neck Squamous Cell Carcinoma primary tumor
    • Hepatocellular carcinoma tumor tissue
    • Ileal mucosa
    • Ileum epithelium
    • Ileum lamina propria
    • Ileum lymphoid aggregates
    • Ileum/Colon mucosa
    • Induced Sputum
    • Inflamed caecum mucosa
    • Inflamed colon mucosa
    • Inflamed descending colon mucosa
    • Inflamed intestinal lamina propria
    • Inflamed left flexure mucosa
    • Inflamed rectum mucosa
    • Inflamed right flexure mucosa
    • Inflamed sigmoid colon mucosa
    • Intestinal granulomas
    • Intestinal lamina propria
    • Intestinal lymphoid aggregates
    • Intestinal mucosa
    • Intestinal mucosa lymphoid follicules
    • Intratumor soft tissue of synovial sarcoma
    • Intratumoral region of tumor-draining/sentinel lymph node - metastatic
    • Invasive margin of tumor soft tissue of synovial sarcoma
    • Jejunal epithelium
    • Jejunal lamina propria
    • Left flexure mucosa
    • Lesional dermis
    • Lesional epidermis
    • Lesional skin
    • Liver
    • Liver metastases peritumoral
    • Liver metastasis intratumoral
    • Liver: hepatic lobules
    • Liver: portal area
    • Lung adenocarcinoma tumor tissue
    • Lung cancer tissue
    • Lung tissue
    • Lymph
    • Lymph node
    • Melanoma peritumoral tissue
    • Melanoma tumor tissue
    • Mesenteric lymph node
    • Metastasis in distant node
    • Metastasis in liver
    • Metastasis in lung
    • Metastasis in ovary
    • Non-inflamed intestinal lamina propria
    • Non-lesional dermis
    • Non-lesional epidermis
    • Non-lesional skin
    • NSCLC Intersection of tumor tissue and normal pulmonary tissue
    • NSCLC peritumoral tissue
    • NSCLC tissue (tumor+stroma)
    • NSCLC tumor islets (nests)
    • NSCLC tumor stroma
    • NSCLC tumor tissue
    • NSCLC Tumor tissue homogenate
    • Oesophageal adenocarcinoma tumor centre
    • Oesophageal adenocarcinoma tumor edge
    • Ovarian cancer tumor tissue
    • Palatine tonsils
    • Pancreatic tissue
    • Pancreatic tumor tissue
    • Pericardial effusion
    • Peripheral bronchial biopsy specimens
    • Peritoneum
    • Peritumoral region of tumor-draining/sentinel lymph node - metastatic
    • Peyer’s patches
    • Plasma
    • Plasma arterial
    • Plasma from cord blood
    • Pleural effusion
    • Prostate cancer tissue
    • Prostate tissue
    • Rectum mucosa
    • Renal tissue
    • Renal tumor capsula
    • Renal tumor margin
    • Renal tumor stroma
    • Renal tumor tissue
    • Right flexure mucosa
    • Seeding metastasis
    • Serum
    • Serum from tumor
    • Sigmoid colon lamina propria
    • Sigmoid colon mucosa
    • Skin
    • Small intestine
    • Small intestine lamina propria
    • Spleen
    • Sputum
    • Squamous cell carcinoma tumor tissue
    • Stroma region of colon
    • Suction Blister Fluids
    • Synovial fluid
    • Synovial membrane
    • Synovial membrane intima
    • Synovial membrane subintima
    • Synovial membrane-around lymphocyte clusters
    • Synovial tissue
    • Thyroid adenoma tumor tissue
    • Thyroid carcinoma tumor tissue
    • Thyroid tissue
    • Transbronchial (alveolar tissue) biopsies
    • Tumor
    • Tumor region of colon
    • Tumor-draining/sentinel lymph node
    • Tumor-draining/sentinel lymph node - metastatic
    • Tumor-draining/sentinel lymph node - non-metastatic
    • Urine
    • 12-hydroxyeicosatetraenoic acid (12-HETE)
    • 15-hydroxyeicosatetraenoic acid (15-HETE)
    • 25-hydroxyvitamin D (25(OH)D)
    • 5-hydroxyeicosatetraenoic acid (5-HETE)
    • 6-Keto-Prostaglandin F1α (6-Keto-PGF1α)
    • 8-Hydroxy-2'-deoxyguanosine (8-OHdG)
    • 8-isoprostane
    • 9a,11b-Prostaglandin F2 (9a,11b-PGF2)
    • Abeta42
    • Adenosine deaminase (ADA)
    • Adiponectin
    • Adipsin
    • Adrenocorticotropic hormone (ACTH)
    • ALA (alpha-linolenic acid)
    • Alanine aminotransferase (ALT)
    • Albumin
    • ALP (Alkaline phosphatase)
    • Alpha-1 antitrypsin
    • Alpha-1 globulin
    • Alpha1-fetoprotein
    • Alpha-2 globulin
    • Alpha2-antiplasmin (A2PI)
    • Alpha2-macroglobulin (a2M)
    • Alpha-tocopherol
    • Amylase
    • Angiopoietin-2
    • Angiostatin
    • anti-HBc
    • Anti-SEA IgE (anti-staphylococcus enterotoxin A)
    • Anti-SEB IgE (anti-staphylococcus enterotoxin B)
    • ApoA-I
    • ApoA-II
    • ApoA-IV
    • ApoB
    • ApoC-III
    • ApoE
    • APRIL
    • Arachidonic Acid
    • Arginase I
    • Ascorbic acid
    • Aspartate aminotransferase (AST)
    • Axl (tyrosine-protein kinase 7)
    • BAFF
    • BAMBI
    • Beta-2-microglobulin
    • Betacellulin (BTC)
    • Beta-globulin
    • b-FGF (basic fibroblast growth factor, FGF2)
    • Bilirubin direct
    • Bilirubin indirect
    • Bilirubin total
    • Blood urea nitrogen
    • Brain natriuretic peptide (BNP)
    • Brain-derived neurotrophic factor (BDNF)
    • C1q (Complement component 1q)
    • C1s (Complement component 1s)
    • C1s inactivator
    • C2 (Complement component 2)
    • C3 (Complement component 3)
    • C3 PA (properdin factor B)
    • C3c (Complement component 3c)
    • C3d (Complement component 3d)
    • C4 (Complement component 4)
    • C9 (Complement component 9)
    • CA125 (cancer antigen 125)
    • CA12-5 (cancer antigen 12-5)
    • CA15-3 (cancer antigen 15-3)
    • CA19-9 (cancer antigen 19-9)
    • Carbamide
    • Carcinoembryonic antigen (CEA)
    • Cardiac Troponin I (cTnI)
    • Carotenoid
    • Cathelicidin (LL-37)
    • cccDNA
    • CCL1 [C-C motif chemokine Ligand 1]
    • CCL11
    • CCL13
    • CCL14 (HCC-1)
    • CCL15
    • CCL16 (HCC-4)
    • CCL17
    • CCL18
    • CCL19
    • CCL2
    • CCL20
    • CCL21
    • CCL22
    • CCL23
    • CCL24
    • CCL25
    • CCL26
    • CCL27 (CATCK)
    • CCL28
    • CCL3
    • CCL4
    • CCL5 [C-C motif chemokine Ligand 5]
    • CCL7
    • CCL8
    • CCP (Cyclic Citrullinated Peptide) antibodies
    • CGRP [Calcitonin Gene Related Protein]
    • Chitinase-3-like protein 1 (YKL-40)
    • Cholesterol
    • Cholesteryl ester
    • Cholinesterase (butyrylcholinesterase)
    • CITP (carboxy-terminal telopeptide of collagen type I)
    • Citrate
    • CKMB (creatine kinase isoenzyme)
    • Collagen IV (C-IV)
    • Complement factor B
    • Cortisol
    • C-reactive protein (CRP)
    • Creatine kinase
    • Creatinine
    • CX3CL1
    • CXCL1
    • CXCL10
    • CXCL11
    • CXCL12
    • CXCL12a (SDF-1a)
    • CXCL13
    • CXCL16
    • CXCL2
    • CXCL3
    • CXCL4
    • CXCL5
    • CXCL6
    • CXCL7
    • CXCL9
    • CYFRA 21.1
    • Cystatin C (CysC)
    • Cysteinyl leukotrienes (Cys-LTs)
    • Cytokeratin18 (CK18)
    • D-dimer (fibrin degradation product)
    • DGLA (dihomo-gamma linolenic acid)
    • DHA (Docosahexaenoic acid)
    • DNAse1
    • DNAse1L3
    • DPA (Docosapentaenoic acid)
    • ECP [Eosinophil Cationic Protein]
    • Elafin
    • Elastin-derived peptide
    • EMMPRIN (CD147)
    • Endotoxin
    • Eosinophil protein Х (EPX)
    • EPA (Eicosapentaenoic acid)
    • Epidermal Growth Factor (EGF)
    • Fas
    • FasL
    • Ferritin
    • FGF
    • FGF-2 ( fibroblast growth factor 2)
    • Fibrin
    • Fibrin Degradation Products (FDP)
    • Fibrinogen
    • FLCs kappa
    • FLCs lambda
    • Flt3‑L
    • Follistatin
    • Free Choline
    • Free Fatty acids (FFA)
    • Free Glycerol
    • Gamma-globulin
    • gamma-Glutamyl Transpeptidase (GGT)
    • GCSF [Granulocyte Colony-Stimulating Factor]
    • GH (growth hormone/somatotropin)
    • Glial cell-derived neurotrophic factor (GDNF)
    • Globulin
    • Glucose
    • Glutathione peroxidase (GSH-PX)
    • Glycoprotein 130 (gp130)
    • Glycyl-proline-dipeptidyl aminopeptidase (GPDA)
    • GMCSF [Granulocyte-Macrophage Colony-Stimulating Factor]
    • GranzymeA
    • GranzymeB
    • Growth-related oncogene (GRO)
    • GSH (reduced glutathione)
    • GSSG (oxidised glutathione)
    • H2O2
    • Haptoglobin
    • hBD-2 (human β-defensin 2)
    • hBD-3 (human β-defensin 3)
    • HBeAg
    • HBsAg
    • HBV DNA
    • HBV RNA
    • HCV RNA
    • HDL-cholesterol
    • HDL-unesterified cholesterol
    • HE4 (Human epididymis protein 4)
    • Hemoglobin
    • Hepatocyte growth factor (HGF)
    • High mobility group box 1 (HMGB1, amphoterin)
    • high sensitive troponin I (hsTnI)
    • Hippurate
    • Histamine
    • HNPs (human neutrophil peptides, defensins)
    • Hyaluronic acid (HA)
    • ICAM
    • IFNa [Interferon Alpha]
    • IFNb
    • IFNg [Interferon gamma]
    • IgA
    • IgE
    • IGF-1 (insulin growth factor 1)
    • IGFBP-2 (insulin like growth factor binding protein 2)
    • IGFBP-3
    • IgG
    • IgG1
    • IgG2
    • IgG3
    • IgG4
    • IgM
    • IL1
    • IL10
    • IL11
    • IL12
    • IL12a (IL12p35)
    • IL12b (IL23p40)
    • IL12p70
    • IL13
    • IL15
    • IL16
    • IL17
    • IL17a
    • IL17af
    • IL17F
    • IL18
    • IL18 BPa
    • IL18BP (Interleukin-18 Binding Protein)
    • IL19
    • IL1a
    • IL1b
    • IL1RA [Interleukin-1 Receptor Antagonist]
    • IL1RAcP
    • IL1RL1 [Interleukin 1 Receptor Like 1]
    • IL2
    • IL20
    • IL21
    • IL22
    • IL23 (p19/p40)
    • IL23p19 (IL23a)
    • IL24
    • IL25
    • IL26
    • IL27
    • IL28a
    • IL29
    • IL2R
    • IL2Ra (CD25)
    • IL3
    • IL31
    • IL32
    • IL33
    • IL34
    • IL35
    • IL36
    • IL37
    • IL4
    • IL-41 (Meteorin-like)
    • IL5
    • IL6
    • IL7
    • IL8 [Interleukin 8]
    • IL9
    • Immune complexes (IC)
    • Immunoreactive LTC4 (iLTC4)
    • Insulin
    • Interferon (IFN)
    • Interferon Alpha 2 (IFNa2)
    • Iron
    • ischemia-modified albumin (IMA)
    • Keratinocyte growth factor
    • KL-6
    • Kynurenine
    • Lactate
    • Lactate dehydrogenase
    • Laminin (LN)
    • LDL-cholesterol
    • Leptin
    • LIF (leukemia inhibitory factor)
    • LIGHT (TNFSF14, CD258)
    • Linoleic Acid
    • Lipase
    • Lipocalin-2
    • LRG (leucine-rich alpha-2 glycoprotein)
    • LTB4
    • LTC4
    • LTD4
    • LTE4
    • Lysozyme
    • Mast cell chymase
    • Mast cell tryptase
    • MCSF
    • MDA (malondialdehyde)
    • MIF
    • MMP1
    • MMP10
    • MMP12
    • MMP13
    • MMP2
    • MMP3
    • MMP7
    • MMP8
    • MMP9
    • Monoamine oxidase (MAO)
    • MSPa (macrophage stimulating protein a)
    • MUFA (Monounsaturated Fatty Acids)
    • Myeloperoxidase (MPO)
    • Myoglobin
    • Neopterin
    • Neurofilament light chain
    • Neuron-specifc enolase (NSE)
    • Neuropeptide Y
    • Neutrophil elastase
    • NGF [Nerve Growth Factor]
    • NGF-beta (beta-nerve growth factor)
    • NLRP3 (Nod-like receptor protein 3 inflammasome)
    • NO
    • Nonesterified Fatty Acid (NEFA)
    • Non-HDL-unesterified cholesterol
    • NT-proBNP (N-terminal brain natriuretic peptide)
    • Oleic Acid
    • Oncostatin-M
    • ONOO (Peroxynitrite)
    • Osteocalcin
    • Osteopontin (OPN)
    • PARC (recombinant human MIP-4)
    • PC-III (type III pre-collagen)
    • PDGF
    • PDGF-BB [Platelet Derived Growth Factor-BB]
    • PDGF-АА
    • Pentraxin-3
    • Perforin
    • Periostin
    • PGE1
    • PGE2 [Prostaglandin E2]
    • Phosphatidylcholine
    • PIIINP (procollagen-III N-terminal peptide)
    • PINP (amino-terminal propeptide of procollagen type I)
    • Plasmin-alpha2-plasmin inhibitor complex (PIC)
    • Plasminogen
    • Plasminogen activator inhibitor-1 (PAI-1)
    • Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)
    • Platelet-Activating Factor (PAF)
    • Pleiotrophin (PTN)
    • PlGF-1 (Placental growth Factor 1)
    • Prealbumin
    • pro-BNP (pro-B-type natriuretic peptide)
    • Procalcitonin
    • Procollagen-3
    • Prolactin (PRL)
    • Prostaglandin D2
    • Prostaglandin F2b (PGF2b)
    • Prostaglandin F2α (PGF2α)
    • Protein carbonyls
    • Protein total
    • PSA (prostate‐specific antigen)
    • P-tau (phosphorylated tau)
    • PUFA (Polyunsaturated Fatty Acids)
    • Resistin
    • Retinol-binding protein (RBP)
    • RF (Rheumatoid Factor)
    • RF-IgM
    • RIPK1 (receptor-interacting protein kinase-1)
    • sAbetaPPbeta
    • sCD163
    • sCD23
    • sCD27
    • sCD30
    • sCD40L
    • SCGF-b (Stem Cell Growth Factor beta)
    • sc-kit (SCFR)
    • Secretory Leukocyte Protease Inhibitor (SLPI)
    • Selenium
    • Serum amyloid A
    • SFA (Saturated Fatty Acids)
    • Sgp130 (Soluble Glycoprotein 130)
    • sIL-18Ra
    • sIL1R1 (Soluble Interleukin-1 Receptor-1)
    • sIL1R2 (Soluble Interleukin-1 Receptor-2)
    • sIL1R3 (Soluble Interleukin-1 Receptor-3)
    • sIL1R4 (Soluble Interleukin-1 Receptor-4)
    • sIL2R
    • sIL2Ra (Soluble Interleukin-2 Receptor subunit alpha)
    • sIL6R
    • sIL7R
    • sILT3
    • SP-40,40 (clusterin)
    • Sphingomyelin
    • sP-selectin
    • Squamous cell carcinoma antigen (SCC)
    • sST2 (Soluble suppression of tumorigenicity-2)
    • Stem Cell Factor (SCF)
    • sTNF-R1
    • sTNF-R2
    • sTREM2 (soluble triggering receptor expressed on myeloid cells 2)
    • Substance P (SP)
    • SuperOxide Dismutase (SOD)
    • Surfactant protein A (SP-A)
    • Surfactant protein D (SP-D)
    • sVEGFR1
    • sVEGFR2
    • Taurine
    • TGFa
    • TGFb
    • TGFb1
    • TGFb1R1
    • TGFb1R2
    • TGFb2
    • TGFb3
    • Thioredoxin 1 (TRX1)
    • Thrombin-antithrombin complex (TAT)
    • Thrombopoietin (TPO, MGDF)
    • Thromboxane B2 (TXB2)
    • Thyroglobulin (TG)
    • Tim-3 (HAVCR2)
    • TIMP1
    • TIMP2
    • Tissue factor
    • Tissue Plasminogen Activator (tPA)
    • Tissue plasminogen activator (tPA)/plasminogen activator inhibitor type I (PAI) complex (tPA/PAI)
    • TL1A (TNFSF15)
    • TNFa
    • TNFb
    • TNFR1
    • TNTHSST (high-sensitivity troponin T)
    • Total bile acid (TBA)
    • Total cholesterol
    • TRAIL (TNF-related apoptosis-inducing ligand)
    • Transferrin
    • Triglyceride
    • Triglycerides
    • Troponin
    • Troponin I
    • Troponin T
    • Tryptase
    • TSLP
    • T-tau (total tau)
    • TWEAK
    • Unesterified cholesterol
    • Urate
    • Urokinase-type plasminogen activator (uPA)
    • VAP-1 (vascular adhesion protein-1)
    • VCAM-1 (vascular cell adhesion molecule-1)
    • VEGF [Vascular Endothelial Growth Factor]
    • VEGF-A
    • VEGF-C
    • VEGF-D
    • VIP [Vasoactive Intestinal Peptide]
    • Vitamin A
    • XCL1
    • α-hydroxybutyrate dehydrogenase (α-HBDH)
    • α-L-fucosidase
    • Activated B-cells
    • Activated Eosinophils
    • Activated suppressor T cells
    • Activated Tc
    • Activated T-cells
    • Activated Th1
    • Activated switched memory B-cells
    • Antigen Presenting Cell (APC)
    • Apoptotic cells
    • Apoptotic eosinophils
    • Atypical memory B-cells
    • Basophils
    • B-cells
    • Bm1-cells
    • Bm2-cells
    • Bm3-cells
    • Bm4-cells
    • Bm5 Early cells
    • Bm5 Late cells
    • Breg cells
    • Cells
    • Central memory T-cells
    • Circulating tumor cells (CTCs)
    • Columnar epithelial cells
    • Dendritic Cells (DC)
    • Dermal dendritic cells
    • Double positive T cells (DP T cells)
    • Double-Negative B-cells
    • Double-negative T cells
    • Double-Positive (DP) memory Th-cells
    • Effector memory T-cells
    • Effector T-cells
    • Eosinophil
    • Epidermal cells
    • Epithelial cells
    • Fibroblast-like synoviocytes
    • Follicular Treg cells (Tfr)
    • gamma-delta T17-cells
    • gamma-delta T-cells
    • Germinal Center B-cells
    • Granulocytic Myeloid-Derived Suppressor Cells (G-MDSC)
    • Hepatocytes
    • Histiocytes
    • IDEC/IDDC
    • Immature B cells
    • Immature transitional B cells
    • Immune cells
    • Immunocytes(T-cells,B-cells,Mast cells)
    • Induced regulatory T cells
    • Inflammatory Dendritic Epidermal Cells (IDEC)
    • Innate lymphoid cells 2 (CRTH2+)
    • Invariant natural killer T-cell
    • Kupffer cells
    • Langerhans Cells (LC)
    • Lymph node-resident Dendritic cell (LNDC)
    • Lymphocytes
    • Macrophages
    • Mast cells
    • Mast cells progenitor
    • Mature B cells
    • Mature Dendritic Cells (DC)
    • Mature Langerhans cells
    • Memory B-cells
    • Memory regulatory T-cells
    • Memory Tc-cells
    • Memory T-cells
    • memory Th17.1-cells
    • memory Th17-cells
    • Memory Th1-cell
    • memory Th22-cells
    • memory Th2-cells
    • memory Th-cells
    • Metachromatic cells (mast cells and basophils)
    • Monocytes
    • Monocytes/macrophages
    • Monocytic Myeloid-Derived Suppressor Cells (M-MDSC)
    • Mononuclear cells
    • Myeloid cells
    • Myeloid Dendritic Cells (mDC)
    • Myeloid Dendritic Cells 1 (mDC1)
    • Myeloid Dendritic Cells 2 (mDC2)
    • Myeloid-Derived Suppressor Cells (MDSC)
    • Naive B-cells
    • Naive regulatory T-cells
    • Naive suppressor T cells
    • Naive Tc-cell
    • Naive T-cells
    • Naive Th1
    • Naive Th-cells
    • Natural Effector B-cells
    • Natural killer T-cells
    • Neutrophil
    • Neutrophil total
    • Neutrophils Nonsegmented
    • Neutrophils Segmented
    • NK [Natural Killer cells]
    • NK1
    • NK17
    • NK2
    • NKT [Natural Killer-like T-cells]
    • Non-memory B cells
    • Non‐switched memory B-cells
    • Pan-leukocytes
    • PBMC (Lymphocytes and Monocytes)
    • PD-L1+ Cell
    • Peripheral blood monocytes
    • Peripheral blood mononuclear MDSCs (PMN-MDSCs)
    • Plasma B-cells
    • Plasmablasts
    • Plasmacytoid Dendritic Cells (pDC)
    • Platelets
    • Polymorphonuclear (PMN) leukocytes
    • Precursor neutrophils
    • Precursor of Germinal Center B-cells
    • Red blood cells
    • Resting class-switched memory B-cells
    • Resting neutrophils
    • Sensory Nerve Endings
    • Squamous cells
    • Stem Cell Memory T cell (Tscm)
    • Suppressor T cells
    • Suppressor T-lymphocytes
    • Switched memory B-cells
    • Tc17-cell
    • Tc1-cell
    • Tc22-cell
    • Tc2-cell
    • Tc9-cell
    • Tc-cells
    • T-cells
    • Tconv cells
    • Tcreg-cells
    • Teff/Treg cell
    • Terminally differentiated effector T cells (EMRA)
    • Tfh17-cells
    • Tfh1-cells
    • Tfh2-cells
    • Tfh-cells (follicular helper T-cells)
    • Th0-cells
    • Th17.1-cells
    • Th17-cells
    • Th1-cells
    • Th22-cells
    • Th2-cells
    • Th9-cells
    • Th-activated
    • Th-cells
    • Th-cells exhausted
    • T-helper lymphocytes
    • TIP-DC (TNF and iNOS-producing dendritic cell)
    • Total cell count
    • Tph-cells (peripheral helper T-cells)
    • Transitional B cells
    • Treg-cells
    • Trm-cells (tissue-resident memory T cells)
    • White Blood Cells (WBC)
  • 35097 values of cytokine/cell concentrations;
  • data extracted from 994 papers/other public sources.

CYTOCON DB Open is developed as a web application based on the ASP.NET MVC framework. It works under Microsoft IIS web server. The data warehouse is a Microsoft SQL Server database. The user interface application is implemented using Telerik Kendo UI and Bootstrap.

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